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FAUC 1036
CAS No. 1869983-83-4
FAUC 1036( FAUC1036 | FAUC-1036 )
Catalog No. M12893 CAS No. 1869983-83-4
A potent, biased allosteric agonist of CXCR3 (pEC50=6.64).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
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Biological Information
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Product NameFAUC 1036
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NoteResearch use only, not for human use.
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Brief DescriptionA potent, biased allosteric agonist of CXCR3 (pEC50=6.64).
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DescriptionA potent, biased allosteric agonist of CXCR3 (pEC50=6.64), selectively induces chemotaxis and receptor internalization, and induces β-arrestin 2 recruitment without any stimulation of G proteins.
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In Vitro——
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In Vivo——
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SynonymsFAUC1036 | FAUC-1036
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PathwayGPCR/G Protein
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TargetChemokine Receptor
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RecptorChemokine Receptor
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Research Area——
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Indication——
Chemical Information
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CAS Number1869983-83-4
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Formula Weight744.933
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Molecular FormulaC45H52N4O6
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Purity>98% (HPLC)
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Solubility——
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SMILES——
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Chemical Nametert-Butyl {(S)-1-[(2,2-diphenylethyl)amino]-1-oxo-6-[(S)-2-(4-oxo-4-phenylbutanoyl)-1,2,3,4-tetrahydroisoquinoline-3-carboxamido]hexan-2-yl}carbamate
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Milanos L, et al. J Med Chem. 2016 Mar 10;59(5):2222-43.
2. Milanos L, et al. Angew Chem Int Ed Engl. 2016 Dec 5;55(49):15277-15281.
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